May 2012, Newsletter
Untitled Document
May 2012 - Issue 2056 The Newsletter Is Also Available HERE!

Our mission in this newsletter is to inform health care professionals about biomimetic hormone replacement therapy, otherwise known as bio-identical hormones and to promote healthy aging and optimal patient management.

WP Articles

Mystery Cases
We have added this new topic to the clinical newsletters. Please submit your professional opinion about these cases that will be presented monthly. What do you think? How would you handle this patient? Please send your diagnosis to This e-mail address is being protected from spambots. You need JavaScript enabled to view it before June 4 and we will share it in next month’s newsletter.

A 9-year-old boy with asthma, marked obesity, and bow legs (genu varum) presents to the emergency department (ED) complaining of left hip and knee pain. He refuses to bear weight on his left leg. His mother reports that the child fell down in the street 2 days ago. The pain is described as mild to moderate in intensity. The patient denies any numbness or tingling in the distal left lower extremity. No skin laceration or bruising is reported by the family. Upon further questioning, the mother admits to having witnessed evolving symptoms over the past 2 months. She describes a worsening limp, decreasing mobility, and increasing left hip and knee pain, without any identified inciting trauma.

The patient was brought to the ED 10 months before this presentation for a similar episode of left knee pain after a vague history of a fall. At that visit, a radiograph of the affected knee demonstrated changes consistent with moderate juvenile Blount disease (arrow). The patient was given a prescription for a nonsteroidal anti-inflammatory drug as needed for pain control and was discharged. The symptoms resolved after only 3 days, and the child was asymptomatic for the following 8 months. He has no previous history of surgery and no known drug allergies, and he is up to date on his immunizations. The patient's mother denies exposure of the child to secondhand smoke. The family history is noncontributory. What is Blount disease and what are the expected radiographic findings?... Read More

Answer to April's Mystery Case:

Response from Drs. Courtney Ridley and Julie Taguchi:

She goes autoimmune every month. She dumps her P4, loses TNFa blockade, spills the usual cytokines released as a part of the menstrual event and gets body aches, low grade temp elevation, flushing, nausea, headache, etc. It fades by days four - five when these mediators fade and by day six when Estrogen goes up expressing TH1 driving down her TH2 response. She has an out of balance immune system anyway based on her reaction to silicone implants. I would not have put silicone in a breast cancer patient with psoriasis. Her story is much more complex I am sure and without a full history I cannot say for certain, but, she needs more Estrogen most likely and probably some cortisone......her gut is probably a mess meaning her biotransformation is off. I would be cleaning all of that up and doing a 24 hour urine test to make sure she is eliminating her Estrogen in the right ration and amounts.

Do you agree with this diagnosis??

 Breast Cancer Rules Rewritten in ‘Landmark’ Study
What we currently call breast cancer should be thought of as 10 completely separate diseases, according to an international study which has been described as a "landmark".

The categories could improve treatment by tailoring drugs for a patient's exact type of breast cancer and help predict survival more accurately.

The study in Nature analysed breast cancers from 2,000 women.

It will take at least three years for the findings to be used in hospitals. Cancer cartography

Researchers compared breast cancer to a map of the world. They said tests currently used in hospitals were quite broad, splitting breast cancer up into the equivalent of continents.

The latest findings give the breast cancer map far more detail, allowing you to find individual "countries".

"Breast cancer is not one disease, but 10 different diseases," said lead researcher Prof Carlos Caldas.

He added: "Our results will pave the way for doctors in the future to diagnose the type of breast cancer a woman has, the types of drugs that will work and those that won't, in a much more precise way than is currently possible."... Read More

Do You Prescribe this Drug that Causes Memory Loss and Diabetes?
T.S. Wiley notes a bit about cholesterol, "Like saturated fat, carbohydrates and grains, most of us get it all wrong when it gets to cholesterol. We’re told to limit our consumption of butter, lard, red meat and eggs, or worse, to go on statins to reduce our blood cholesterol levels, but yet, our ancestors seem to have thrived on those foods without the predicted heart problems.

“Seeing the opportunity, the pharmacology industry did a really good job of scaring us to death about high cholesterol and dietary cholesterol intake."

"There’s cholesterol all over your body as you read this. It’s an essential constituent of all the cells of your body and also metabolizes all the sex hormones and fat soluble vitamins like vitamin A, D, E and K. Without it, you’d be dead in no time. Also note that if you consume more cholesterol in your diet, your body will down regulate its own production to match its needs so this way you don’t get too much of it. The opposite happens when you reduce your consumption or take drugs to reduce it, your body up-regulates the production and tries to make more for what’s missing."

The Food and Drug Administration (FDA) added new safety warnings to cholesterol-reducing statin drugs on Wednesday, noting increased risks of Type 2 diabetes and memory loss for patients who take the medications.

The changes to the prescribing information apply to the class of statins, including many popularly prescribed drugs such as Lipitor (atorvastatin), Crestor (rosuvastatin), Zocor (simvastatin) and Vytorin (simvastatin/ezetimibe). The new warnings are based on results from the latest clinical trials and reports of adverse events from patients, physicians and drugmakers... Read More

Are your Patients at Risk for Serious Eye Disease?
T. S Wiley notes, “The first line of defense against osteoporosis is natural, transdermal, bio-identical biomimetic hormone replacement such as the Wiley Protocol. This will do what none of these drugs can do: revive your bones”. The drugs discussed in the following article are contra-indicated for women on the Wiley Protocol.

Drugs that are commonly used to prevent osteoporosis may increase the risk of serious inflammatory eye disease in first-time users, found an article in CMAJ (Canadian Medical Association Journal).

Oral bisphosphonates, the most commonly prescribed class of drugs used to prevent osteoporosis, have been linked to adverse events such as unusual fractures, irregular heartbeat, and esophageal and colon cancer. Some case reports have shown an association between these drugs and anterior uveitis and scleritis, inflammatory eye diseases that can seriously affect vision.

Researchers from the Child and Family Research Institute and the University of British Columbia, Vancouver, BC, undertook a study to examine and quantify the risk associated with uveitis or scleritis and oral bisphosphonates because the literature is limited. They included 934 147 people in British Columbia who had visited an ophthalmologist between 2000 and 2007. Of the total, 10 827 were first-time users of bisphosphonates and 923 320 were nonusers ... Read More

nl_shift_work_teens_linked Which Hormone Helps Heart Failure?
A new research analysis finds that testosterone supplements helped heart failure patients breathe better and exercise more without significant side effects.

According to study results published in Circulation Heart Failure, an American Heart Association journal, those who received supplemental testosterone scored 50 percent better in a six-minute walking test than those receiving a placebo.

But researchers cautioned that the findings are preliminary and larger studies are needed.

“We don’t want patients and their loved ones rushing to buy testosterone supplements online, or physicians to misinterpret the findings. First the results need to be corroborated in large clinical trials,” said Justin A. Ezekowitz, M.D., M.Sc., study author and assistant professor and director of the Heart Function Clinic at the University of Alberta in Edmonton, Canada. Researchers analyzed four randomized clinical trials of patients with moderate to severe chronic heart failure. Patients were given commercial testosterone supplements by injection, patch or gel.

Study Highlights:

Testosterone supplements helped stable heart failure patients with moderate to severe disease breathe better and exercise more, according to a review of four previous studies... Read More

Which Hormone Protects after TBI?
T.S. Wiley testified before the Senate in 2007 discussing the successful use of compounded progesterone for TBI in the Military.

With more than 1.7 million people sustaining a traumatic brain injury each year, the need to identify processes to limit inflammation and subsequent damage is critical. Approximately 275,000 people are hospitalized annually with traumatic brain injury, leaving 85,000 with long-term disabilities and taking the lives of more than 50,000. More than 5 million people live with disabilities caused by traumatic brain injuries, often the result of car accidents and falls. Direct and indirect costs exceed billion.

Dr. Joshua Gatson, Assistant Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas, investigates biomarkers and novel therapies for traumatic brain injury. His previous work has shown that estrone, one of the three naturally occurring estrogen hormones in the body, has shown some promise in reducing inflammation and cell death in the brain. His latest study is the first to demonstrate estrone provides those anti-inflammatory and antioxidant capabilities after traumatic brain injury. It is likewise the first to reveal the cellular pathways that are involved. His findings were presented April 22, 2012 during Experimental Biology 2012 in San Diego, CA.

The study, conducted in male rats, compared 0.5 mg of estrone to a placebo, both given 30 minutes after the injury. It demonstrated that estrone is involved in promoting brain-derived neurotrophic factor (BDNF), which promotes cell survival. "BDNF, one of the main growth factors that regulates repair following injury, is actually increased following treatment with estrone after brain injury," said Gatson, who administered the injections within 30 minutes of the injury. "So if you give this drug shortly after injury, it is thought to increase repair mechanisms."... Read More

nl_shift_work_teens_linked What can your Patients do to Protect against Breast Cancer if they are BRCA1 Carriers?
T.S. Wiley is and always will be a strong proponent of breastfeeding babies into toddler hood, primarily as the single strongest action against preventing breast cancer.

In her book, "Sex, Lies and Menopause", she notes the "collaborative reanalysis of individual data" published in July 2002 in the Lancet, from 47 studies in 30 countries, including 50,302 women with breast cancer and 96,973 women without the disease. "Researchers concluded that if women in developed nations like the United States breast fed nine months longer than the norm, which is three months, breast cancer deaths would be reduced by 25,000 lives. Furthermore, and most importantly, if women breast fed twelve months longer, or fifteen months in total, as is the norm in developing nations, lives saved from breast cancer each year would approach 50,000. Since only about 47,000 of us are expected to die from breast cancer this year, that's all of us who would be saved".


Breastfeeding has been inversely related to breast cancer risk in the general population. Clarifying the role of breastfeeding among women with a BRCA1 or BRCA2 mutation may be helpful for risk assessment and for recommendations regarding prevention. We present an updated analysis of breastfeeding and risk of breast cancer using a large matched sample of BRCA mutation carriers.


We conducted a case-control study of 1,665 pairs of women with a deleterious mutation in either BRCA1 (n = 1,243 pairs) or BRCA2 (n = 422 pairs). Breast cancer cases and unaffected controls were matched on year of birth, mutation status, country of residence and parity. Information about reproductive factors, including breastfeeding for each live birth, was collected from a routinely administered questionnaire. Conditional logistic regression was used to estimate the association between ever having breastfed, as well as total duration of breastfeeding, and the risk of breast cancer... Read More

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New book recommendation:
Truth, Lies and Controversy
by Peter C Gotzsche

Book Recommendation:

T.S. Wiley hosts new Radio Show on
Do you want to understand what you hear on the news, read in the paper and see on the Internet about science, medicine and your health? Are you confused about the issues surrounding cancer, diabetes, aging and sleep? It’s really hard to sort out the truth. Listen to real experts in all fields of science and medicine debate the top medical news alerts with TS Wiley. Choosing the wrong path could be expensive, scary or, even, life-threatening when it comes to your health. So….What you need is A Second Opinion.

Risk/Benefit Ratio: Is the Cure Worth the Kill?
Host TS Wiley interviews mainstream oncologist Julie Taguchi from Sansum Clinic in Santa Barbara, California on the memory loss attendant with estrogen deprivation and chemotherapy. In the interview they also cover the validity of big pharma testing on oncology drugs versus no treatment at all. This is a candid and frank interview with someone on the inside of the standard of care in breast cancer treatment.
This isn’t a show you want to miss!
Click Here to Hear the Show
T.S. Wiley's newly published paper in the AIP Physics Journal AIP Advances (Vol. 2, Issue 1)
"The theory of modulated hormone therapy for the treatment of breast cancer in pre- and post-menopausal women", has been published online on March 29, 2012
Read the abstract
Read the Paper

New! Bianca Tyler interviews TS Wiley

TS Wiley on Holy Hormones


Two Days Back on Earth

Conference Glendale, CA May 12-13, 2012
Hilton Hotel
100 W Glenoaks Blvd.
Glendale CA 91201
Rooms 9.00

The 6th Annual 2012 AustralAsian Conference in Anti-Ageing & Aesthetic Medicine
August 18-19, 2012
Melbourne, Australia

Two Days Back on Earth
is coming to the East Coast August 25-26, 2012
The Siena Hotel
1505 East Franklin Street
Chapel Hill, NC 27514
Rooms 5.00

National Community Pharmacists Show October 13-17, 2012
San Diego, CA
Wiley Exhibits

For seminar information and registration please contact your sales rep:

Nancy Juniper This e-mail address is being protected from spambots. You need JavaScript enabled to view it
(ME, NY, PA, VA, OH, KY, NC, SC, GA, FL, IN, RI, CT, NJ, DE, MD, WV, NH, VT, MA, HI)

Julie Meraz
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(WA, OR, CA, MT, ID, WY, ND, SD, NE, MN, IA, WI, MI, AK)

Marty Tricoglou This e-mail address is being protected from spambots. You need JavaScript enabled to view it
(AZ, UT, NM, CO, KS, OK, TX, MO, AR, LA, IL, AL, MS, TN, NV)

Eating GMO Foods Can Cause Cancer and Infertility and Make you Less Human

Food Matters

Questioning Organic Egg Labeling Standards

Most Astonishing Health Disaster of the 20th Century

Sugar Coated Control

Egg-making Stem Cells Found in Adult Ovaries
As discussed in our April Consumer newsletter

Cut Poison Burn Official Trailer

Click for larger picture
Wiley Protocol On Twitter
Wiley Protocol On Face Book
Please visit our new Face Book page with many new pictures. Please visit, like and share with others and we will reciprocate. Thanks.

Wiley Protocol Pharmacist Lee Neal from Medicine Mart Pharmacy in Yakima WA (link to him) has been providing the Wiley Protocol to patients in Washington state since 2008.

Interview with TS Wiley
Part 3 By Dr Susan Padrad

Interview with TS Wiley
Part 4 By Dr Susan Padrad
“I was originally referred to Wiley by Dr Richard Wilkinson. At the time I was concerned about the political landscape with increased regulation over intra-state commerce, so wanted to make sure I was able to provide this protocol to my provider’s patients. I attended the “Two Day Back on Earth” conference a few times with some of my prescribers.

As a pharmacist the Wiley Protocol is the only system I have found that actually “mimics” the actual female rhythm. It’s wise to listen to what the body is already doing. I was already having problems with what I feel is the over use of birth control pills for every ailment in younger women. There was never any discussion of testing of estrogen or progesterone levels. It seemed absurd to me to put everyone on the pill. I’d like to see more use of this protocol for younger women to address what are obviously unbalanced hormones. At this time my Wiley business consists of peri and menopausal women. I’m glad that Wiley actually restores and the only protocol that cycles that I’ve seen.

As a business man this protocol has improved our gross profits which I’m very happy about. As a pharmacist I find the women are happier on this protocol than any other BHRT, which we compound. We also have a number of male patients starting on the WP. It’s logical to me that it’s a better approach. So many of my customers come in to see me to tell me how much better their quality of life is on the WP. This is very rewarding.

I, like most of my peers, would like to see more natural substances used for what ails us. Unfortunately, big pharma won’t support what it can’t control, patent and make billions on.”

Interview with a Wiley Protocol Provider:
We asked Dr. Courtney Ridley, OBGYN, MD who practices in Dallas, TX how she found out about the Wiley Protocol and why she has chosen it as her preferred BHRT regimen for 1200 patients. In addition she shared with us some of her most remarkable Wiley stories. Dr. Ridley is also part of the faculty for our Two Days Back on Earth conferences.

“I have been prescribing all forms of BHRT for over 20 years. When I started all we had was Premarin. It wasn’t until the 1990’s that we had any bio-identicals in the form of Bi-Est and Ti-est. Then when the WHI came out in 2002, and the whole Premarin thing exploded, the only thing left was BHRT. I started by prescribing low static doses of bio-identicals in all forms, patches, troiches, creams, etc. This worked reasonably well, but what I started noticing is any positive results they produced, wore off by six months to a year. I found that I had to increase the dose, only to find the same issues a year later. I know now that this was because of “receptor resistance”, but I didn’t know that then.

As I started to raise the estrogen, I started to see abnormal bleeding and changes in the mammograms. Plus half the patients still asked me, is this all there is? They still had libido issues, poor vaginal health, low self-esteem, brain fog, a slow decline in bone density and an overall lack of vitality. It was 2005, I was already working at a functional medicine clinic where we did everything else physiologically and I was thinking maybe we weren’t getting what we wanted, because we weren’t giving the hormones to the women in a way that mimics their natural rhythm.

About a month later I heard T.S. Wiley at ACAM when she was the keynote speaker. I ordered her CD, called “Rhythmically Dosed Hormones” and the lights went on for me. Here was the missing piece. I got very excited. I read T.S. Wiley’s books and I started trying to use it; asking pharmacists if they could make it. This was before I knew that you could actually purchase it.

It was a call from a celebrity, who specifically asked for the Wiley Protocol, that I learned it was available. She was excited that I was very well versed in it. Being able to help this prominent patient secured me a new job. Then I contacted the Wiley office, learned I could prescribe it to a registered pharmacy and I was off and running. A win-win situation for all!

It was about this time that Suzanne Somers’s interviewed T. S. Wiley and Dr. Julie Taguchi for her book, Ageless. For me, Wiley represented a more physiological approach to giving hormones in a way that mimicked the normal physiology, in a rhythm. My patients started reporting that they felt like themselves again. I heard over and over, I feel like a ‘girl’ again, I’m buying lingerie again. My libido is back! I was just excited because the reasons I switched to Wiley proved to be true.

Over time, working with TS, she saw that I saw what she saw, and that’s when the formal education began. Working with her helped me understand what it meant to be in my profession.

When I understood the estrogen and progesterone connection and then I made the HPA connection to the adrenals and particularly progesterone to the adrenals, then I completely understood the whole gamut of issues that I’ve seen as a gynecologist. Understanding the importance of ‘rhythm’ was key. Without this rise and fall you lose your receptors. Then nothing works.

What really helped me understand the whole rhythmic dosing thing is when I started looking at RANK/RANKL (Receptor Activator of Nuclear factor Kappa-B Ligand) in relationship to the bones.

It was also about that time that more and more of my patients came in with remarkable reverses in bone loss on their bone density tests. I’m talking about 8-18% bone growth in a year. I had two 70 year old patients that had come to see me specifically because they had osteoporosis and nothing was working. As time went on, I saw this more and more with all of my Wiley patients. Wiley stimulates RANK/RANKL and reverses osteroporosis!!!

I started putting together that the calcifications showing up on mammograms were there because the women were losing calcium in the bones when they lost their rhythm. Plus there’s an inflammatory response going on because progesterone isn’t progesterone and that’s why you’re spilling calcium. It made sense because progesterone stimulates the osteoblasts to put calcium back into the bones and grow bones. So if this is working in the bones, it’s working in the breasts and chances are you would then get protection of the breasts and the damage doesn’t progress. And you can’t receive the progesterone without the estrogen peak. For me this was crucial and it shows that the breast cancer issue is inflammation. It has nothing to do with estrogen, except for the fact that high doses of estrogen can block RANKL. But when you have low estrogen that’s when RANKL rages and everything gets inflamed. Now you are out of progesterone and you become auto-immune and more inflamed. What’s required to activate and maintain receptor roll-over is the rhythm. Without renewing the receptors every cycle they just go insensitive. This is why statically dosed hormones stop working.

I have lots of men on the WP for Men. Before Wiley, I had been using creams and injections for a decade. It worked for six months and then their levels would bottom out, their testicles start to shrink, they’d lose the effects, start diverting it to estrogen and then you had to start blocking the estrogen, etc.

I had a classic case with one specific male patient. Young guy 40’s highly stressed with really low testosterone. He had, had trouble with his prostate, some urinary urgency and delayed stream and hair loss from some of the static testosterone he was using. I put him on Wiley and everything got better in the first three months and this was on the “winter dose”. His only complaint was, not having enough ‘wood’ so he wanted to go back on the shots. His DHT was 200, his testosterone was 450, and his estrogen levels were really low. I tried to tell him that Wiley increases with each season and it would get better, but he was determined to go back onto the shots. So he goes back on the shots and comes to see me three months later and his testosterone was 827. He had a little bit more wood but his DHT went down to 50, his estrogen went up by 30%, his hair loss came back and his urinary problems recurred. It was obvious to me that the rhythmic dosing allowed him to get better conversion to DHT which helped him not lose hair, helped him not convert to estrogen and stabilized his prostate. If he would have just waited three more months he would have gotten the wood he wanted. He was just impatient. So he comes back and decides to stay on the static dose for another three months, even though his labs were the same and he still had the same problems. I told him now he’s developing receptor resistance from the static doses. In the fall he gets back on Wiley. This is a classic case of why Rhythmic Dosing is just as important for men.”

- Mike Adams

T.S. Wiley Books. For More Information Call 1-800-929-WILEY
Lights Out By T.S. Wiley Sex Lies And Menopause By T.S. Wiley
Lights Out
This fascinating, thought-provoking study discusses the central role of sleep in our lives. After probing the scientific literature, T.S. Wiley and Formby, researchers at the Sansum Medical Research Institute, conclude that, "the disastrous slide in the health of the American people corresponds to the increase in light-generating night activities and the carbohydrate consumption that follows.



Sex Lies and Menopause
Turning thirty years of medical and cultural wisdom on its head, Sex, Lies, and Menopause challenges both the medical establishment and modern feminists to prove that menopause does not have to be deadly.


View Reader Reviews!
F.Y.I... We have been told that there are many pharmacies around the country claiming to make the Wiley Protocol. Unless your hormones come in our color coded packaging (green and purple for women, blue and burgundy for men), it says Wiley all over and the pharmacy has our sign in their window, they have not registered with us to make the authentic Wiley Protocol. You would be getting a generic product that will not stand up to federal scrutiny for scientific study.

Please make sure your provider abides by our patent and trademarks and sends your prescription to a Wiley Registered Pharmacy.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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The Wiley Protocol System For Providers And Pharmacists

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